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The National Magnetic Resonance Facility at Madison (NMRFAM) is a resource for biomolecular nuclear magnetic resonance (NMR) spectroscopy and related techniques that aims to expand the frontiers of biomolecular NMR spectroscopy through technology, research, and development programs.

| Become an NMRFAM Collaborator | Become an NMRFAM User |

Learn more about how we can help advance your research in the following areas:

Structural Biology
Small Molecules
High-Throughput Methods
Protein Production and Labeling

Research Center Focus

What is NMRFAM

The National Magnetic Resonance Facility at Madison (NMRFAM) is a Biomedical Technology Research Resource (BTRR), a National Institutes of Health (NIH) / National Institute of General Medical Sciences (NIGMS)-funded, shared instrumentation laboratory located at the University of Wisconsin-Madison Department of Biochemistry.

In addition to assisting users in their research, NMRFAM actively seeks collaborative projects that present substantial technical challenges and serve to drive the development of the Center’s Technology Research and Development (TR&D) Projects.

NMRFAM’s Current TR&D Projects

  • Automation in NMR data collection, spectral analysis and assignment, and structure determination of small- and moderate-sized proteins and RNA molecules.
  • Determination of the structure, dynamics, and functional properties of challenging proteins and nucleic acids and their complexes by NMR and SAXS approaches.
  • NMR-based studies of metabolomics and natural products including LC-MS solid-phase extraction of molecules of interest.

NMRFAM’s Grants and Funding Sources

Become an NMRFAM User
Contacts | Map | Policy
Instrumentation w/Rates
Pulse Programs
Remote Access to NMRFAM
Spectrometer Live Calendar
Sundial (Request NMR Time)
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Biochem 800 – Practical Nuclear Magnetic Resonance Theory

Biochem 801 – Biochemical Applications of Nuclear Magnetic Resonance

"The Future of NMR-Based Metabolomics, Current Opinion in Biotechnology (2017), pp. 34-40

Workshop "Ultrahigh Field NMR and MRI: Science at a Crossroads" November 12-13, NIH

Documents on the use of the Bruker-Axs Nanostar,SAXS instrument and analysis of SAXS data are now available.

NMRFAM-SPARKY Distribution - the popular NMR analysis program SPARKY recompiled (including updated python and Tcl/Tk) with incorporation of PINE-Sparky, enhancements to import/export to the structural analysis program CYANA, and other useful python extensions.

ADAPT-NMR Enhancer: Complete Package for Reduced Dimensionality in Protein NMR Spectroscopy

RNA-PAIRS: RNA Probabilistic Assignment of Imino Resonance Shifts

PACSY, a Relational Database Management System for Protein Structure and Chemical Shift Analysis 

 

Donate to NMRFAM. US tax-deductible donation can be made to NMRFAM
Please write check payable to "UW Foundation, Account 112152802"  
And mail to: 
Attn: Sarah Lynn Traver Saunders
Associate Administrative Program Specialist 
University of Wisconsin-Madison 
433 Babcock Drive 
Madison, WI 53706 
Tel: 608-265-2507 or email 

 

1st: Lai Bergeman 
Rm 171; Phone 262-3173

2nd: Milo Westler
Rm B160; Phone 263-9599

3rd: Mark Anderson
Rm B224; Phone 265-3303

4th: Marco Tonelli
Rm B160; Phone 263-9493

5th: John Markley
Rm 171A; Phone 263-9349

We welcome your questions and feedback!

NMRFAM Established 1987