Biochem 800:
The lecture
notes are available (UW only) as Acrobat
Reader PDF files (also available as postscript files and as zipped
files).
Scope of the course: study of multipulsed, multinuclear, and multidimensional NMR spectroscopy; emphasis on the vector and product operator formalisms for the analysis of modern pulse sequences.
Course format: (2 credits) lecture and discussion; grades to be based on participation and problem sets.
Topics to be covered:
Coherence and Magnetization
Radio Frequency (Rf) Excitation
Chemical Shifts
Signal Detection
Fourier Transformation
Coherence Transfer Pathways and Phase Cycling
Pulsed Field Gradients
Scalar Coupling
Product Operator Formalism
Coherence Transfer
Isotope Directed Editing
Two-Dimensional NMR
Multi (>2)-Dimensional NMR
1H, 13C, and 15N Triple Resonance 3d and 4d NMR
Pulse Concatenation and Sequence Optimization
Relaxation
Course materials: lecture_notes and literature articles.