MARKLEY LAB
 
    
John L. Markley
 

Publications:

  
  2005  
     
  G.A. Zornetzer, R.D. White, J.L. Markley, B.G. Fox "Preparation of isotopically labeled spinach acyl-acyl carrier protein for NMR structural studies," Protein Exp. Purif. available online (2005).  
     
  R.K. Andjus, Z. Dzakula, J.L. Markley, S. Macura "Brain energetics and tolerance to anoxia in deep hypothermia," Ann. N.Y. Acad. Sci. 1048, 10-35 (2005).  
     
  J. Song, R.C. Tyler, M.S. Lee, E.M. Tyler, J.L. Markley "Solution structure of isoform 1 of Roadblock/LC7, a light chain inthe dynein complex," J. Mol. Biol. 354, 1043-1051 (2005).  
     
  H . Blad, N.J. Reiter, F. Abildgaard, J.L. Markley, S.E. Butcher "Dynamics in the U6 RNA intramolecular stem loo: II. NMR analysis of metal binding and conformational exchange on the microsecond time scale," J. Mol. Biol. 353, 540-555 (2005).  
     
  K. Uchida, J.L. Markley, M. Kainosho "Carbon-13 NMR method for the detection of correlated hydrogen exchange at adjacent backbone peptide amides and its application to hydrogen exchange in five anti-parallel beta-strands within the hydrophobic core of Streptomyces subtilisin inhibitor (SSI,)" Biochemistry 44, 11811-11820 (2005).  
     
  Q. Zhao, J. Song, Z. Jin, V. Danilova, G. Hellekant, J.L. Markley "Structural and functional consequences of inserting two residues into a solvent-exposed loop of the sweet protein brazzein," Biochem. Biophys. Res. Commun. 325, 256-263 (2005).  
     
  S. Singh, C.C. Cornilescu, R.C. Tyler, G. Cornilescu, M. Tonelli, M.S. Lee, J.L. Markley "Solution structure of a late embryogenesis abundant (LEA) protein from Arabidopsis thaliana, a cellular stress related protein," Protein Sci. 14, 2601-2609 (2005).  
     
  Y.K. Chae, K. Lee, J.L. Markley "1H, 15N and 13C resonance assignment of a protein involved in the autophagy process, At4g21980.1 from Arabidopsis thaliana," J. Biomol. NMR 32, 337 (2005).  
     
  J. Song, Q. Zhao, M.S. Lee, J.L. Markley "1H, 15N and 13C resonance assigments of the putative Bet v 1 family protein At1g24000.1 from Arabidopsis thaliana," J. Biomol. NMR 32, 335 (2005).  
     
  F.C. Peterson, B.L. Lytle, S. Sampath, D. Vinarov, E. Tyler, M. Shahan, J.L. Markley, B.F. Volkman "Solution structure of thioredoxin h1 from Arabidopsis thaliana," Protein Sci. 14, 2095-2102 (2005).  
     
  E. Bitto, C.A. Bingman, S.T.M. Allard, G.E. Wesenberg, D.J. Aceti, R.L. Wrobel, R.O. Frederick, H. Sreenath, F.C. Vojtik, W.B. Jeon, C.S. Newman, J. Primm, M.R. Sussman, B.G. Fox, J.L. Markley, G.N. Phillips Jr. "The structure at 2.4 A resolution of the protein from gene locus At3g21360, a putative FeII/2-oxoglutarate-dependent enzyme from Arabidopsis thaliana," Acta Cryst. F61, 469-472 (2005).  
     
  V. Stolc, M.P. Samanta, W. Tongprasit, H. Sethi, S. Liang, D.C. Nelson, A. Hegeman, C. Nelson, D. Rancour, S. Bednarek, E.L. Ulrich, Q. Zhao, R.L. Wrobel, C.S. Newman, B.G. Fox, G.N. Phillips, Jr., J.L. Markley, M.R. Sussman "Identification of novel transcribed sequences in Arabidopsis thalianan using high-resolution genome tiling arrays," Proc. Natl. Acad. Sci. USA 102, 4453-4458 (2005).  
     
  J. Song, R.C. Tyler, R.L. Wrobel, R.O. Frederick, F.C. Vojtek, W.B. Jeon, M.S. Lee, J.L. Markley "Solution structure of At3g04780.1-des15, an Arabidopsis thaliana ortholog of the C-terminal domain of human thioredoxin-like protein," Prot. Sci. 14, 1059-1063 (2005).  
     
  D.A. Vinarov, J.L. Markley "High-throughput automated platform for NMR-based structural proteomics," Exp. Rev. Prot. 2, 49-55 (2005).  
     
  R.C. Tyler, H.K. Sreenath, D.J. Aceti, C.A. Bingman, S. Singh, J.L. Markley, B.G. Fox "Auto-induction medium for the production of [U-13C, U-15N]-labeled proteins for NMR screeing and structure determination," Prot. Exp. Purif. 40, 268-278 (2005).  
     
  W.F. Vranken, W. Boucher, T.J. Stevens, R.H. Fogh, A. Pajon, M. Llinas, E. Ulrich, J.L. Markley, J. Ionides, E.D. Laue "The CCPN data model for NMR spectroscopy: development of a software pipeline for HTP projects," Proteins 59, 687-696 (2005).  
     
  R.C. Tyler, D.J. Aceti, C.A. Bingman, C.c. Cornilescu, B.G. Fox, R.O. Frederick, W.B. Jeon, M.S. Lee, C.S. Newman, F.C. Peterson, G.N. Phillips, Jr., M.N. Shahan, S. Singh, J. Song, H. Sreenath, E.M. Tyler, E.L. Ulrich, D.A. Vinarov, F.C. Vojtek, B.F. Volkman, R.L. Wrobel, Q. Zhao, J.L. Markley "Comparison of cell-based and cell-free protocols for producing target proteins from the Arabidopsis thaliana genome for structural studies," Proteins 59, 633-643 (2005).  
     
  C.J. Oldfield, E.L. Ulrich, Y.G. Cheng, A.K. Dunker, J.L. Markley "Addressing the intrinsic disorder bottleneck in structural proteomics," Proteins 59, 444-453 (2005).  
     
  N. Sugimori, T. Torizawa, D.J. Aceti, S. Thao, J.L. Markley, M. Kainosho "1H, 13C and 15N backbone assignment of a 32 kDa hypothetical protein from Arabidopsis thaliana, At3g16450.1," J. Biomol. NMR 30, 357-358 (2005).  
     
  T.E. Malone, S.E. Madson, R.L. Wrobel, W.B. Jeon, N.S. Rosenberg, K.A. Johnson, C.A. Bingman, D.W. Smith, G.N. Phillips, Jr., J.L. Markley, G.G. Fox "X-ray structure of Arabidopsis At2g06050, 12-oxophytodienoate reductase isoform 3," Proteins 58, 243-245 (2005).  
     
  F.M. Assadi-Porter, F. Abildgaard, H. Blad, C.C. Cornilescu, J.L. Markley "Brazzein, a small sweet protein: effects of mutations on its structure, dynamics and functional properties," Chem. Sens. 30, i90-i91 (2005).  
     
  I.-J. Lin, E.B. Gebel, T.E. Machonkin, W.M. Westler, J.L. Markley "Changes in hydrogen-bond strengths explain reduction potentials in 10 rubredoxin variants," Proc. Nat. Acad. Sci. 102, 14581-14586 (2005).  
     
  T.E. Machonkin, W.M. Westler, J.L. Markley "Paramagentic NMR spectroscopy and density functional calculations in the analysis of the geometric and electronic structures of iron-sulfur proteins," Inorg. Chem. 44, 779-797 (2005).  
     
  J.F. Doreleijers, A.J. Nederveen, W. Vranken, J. Lin, A.M.J.J. Bonvin, R. Kaptein, J.L. Markley, E.L. Ulrich "BioMagResBank databases DOCR and FRED containing converted and filtered sets of experimental NMR restraints and coordinates from over 500 protein PDB structures," J. Biomol. NMR 32, 1-12 (2005).  
     
  A.J. Nederveen, J.F. Doreleijers, W. Vranken, Z. Miller, C.A.E.M. Spronk, S.B. Nabuurs, P. Güntert, M. Livny, J.L. Markley, M. Nilges, E.L. Ulrich, R. Kaptein, A.M.J.J. Bonvin "RECOORD: A recalculated coordinate database of 500+ proteins from the PDB using restraints from the BioMagResBank," Prot. Struct. Funct. Bioinf. 59, 662-672 (2005).  
     
  L. Wang, H.R. Eghbalnia, A. Bahrami, J.L. Markley "Linear analysis of carbon-13 chemical shift differences and its application to the detection and correction of errors in referencing and spin system identifications," J. Biomol. NMR 32, 13-22 (2005).  
     
  H.R. Eghbalnia, L. Wang, A. Bahrami, A. Assadi, J.L. Markley "Protein energetic conformational analysis from NMR chemical shifts (PECAN) and its use in determining secondary structural elements," J. Biomol. NMR 32, 71-81 (2005).  
     
  S. Singh, M. Tonelli, R.C. Tyler, A. Bahrami, M.S. Lee, J.L. Markley "Three-dimensional structure of the AAH26994.1 protein from Mus musculus, a putative eukaryotic Urm1," Prot. Sci. 14, 2095-2102 (2005).  
     
  H.R. Eghbalnia, A. Bahrami, L. Wang, A. Assadi, J.L. Markley "Probabilistic identification of spin systems and their assignments including coil-helix inference as output (PISTACHIO)," J. Biomol. NMR 32, 219-233 (2005).  
     
  H.R. Eghbalnia, A. Bahrami, M. Tonelli, K. Hallenga, J.L. Markley "High resolution iterative frequency identification for NMR (HIFI-NMR) as a general strategy for multidimensional data collection," J. Am. Chem. Soc. 127, 12528-12536 (2005).  
     
     
  2004  
     
  L. Skjeldal, F.C. Peterson, J.F. Doreleijers, L.A. Moe, J.D. Pikus, W.M. Westler, J.L. Markley, B.F. Volkman, B.G. Fox "Solution structure of T4moC, the Rieske ferredoxin component of the tolulene 4-monooxygenasee complex," J. Biol. Inorg. Chem. 9, 945-953 (2004).  
     
  J. Song, Q. Zhao, S. Thao, R.O. Frederick, J.L. Markley "Letter to the Editor: Solution structure of a calmodulin-like calcium-binding domain from Arabidopsis thaliana," J. Biomol. NMR 30, 451-456 (2004).  
     
  B.L. Lytle, F.C. Peterson, S.H. Qiu, M. Luo, Q. Zhao, J.L. Markley, B.F. Volkman "Solution structure of a ubiquitin-like domain from tubulin-binding cofactor B," J. Biol. Chem. 279, 46787-46793 (2004).  
     
  C.A. Bingman, K.A. Johnson, F.C. Peterson, R.O. Frederick, Q. Zhao, S. Thao, B.G. Fox, B.F. Volkman, W.B. Jeon, D.W. Smith, C.S. Newman, E.L. Ulrich, A. Hegeman, M.R. Sussman, J.L. Markley, G.N. Phillips Jr. "Crystal structure of the protein from gene At3g17210 of Arabidopsis thaliana," Proteins: Struct. Func. Bioinf. 57, 218-220 (2004).  
     
  D.W. Smith, K.A. Johnson, C.A. Bingman, D.J. Aceti, P.G. Blommerl, R.L. Wrobel, R.O. Frederick, Q. Zhao, H. Sreenath, B.G. Fox, B.F. Volkman, W.B. Jeon, C.S. Newman, E.L. Ulrich, A.D. Hegeman, T. Kimball, S. Thao, M.R. Sussman, J.L. Markley, G.N. Phillips Jr. "Crystal structuure of At2g03760, a putative steroid sulfotransferase from Arabidopsis thaliana," Proteins: Struct. Funct. Bioinform. 57, 854-857 (2004).  
     
  Q. Zhao, R. Frederick, K. Seder, S. Thao, H. Sreenath, F. Peterson, B.F. Volkman, J.L. Markley, B.G. Fox "Production in two-liter beverage bottles of proteins for NMR structure determination labeled with either 15N- or 13C-15N," J. Struct. Funct. Genomics 5, 87-93 (2004).  
     
  G. Cornilescu, C.C. Cornilescu, Q. Zhao, R.O. Frederick, F.C. Peterson, S. Thao, J.L. Markley "Solution structure of a homodimeric hypothetical protein, At5g22580, a structural genomics target from Arabidopsis thaliana," J. Biomol. NMR 29, 387-390 (2004).  
     
  Y.K. Chae, H. Im, Q. Zhao, J.H. Doelling, R.D. Vierstra, J.L. Markley "Prevention of aggregation after refolding by balanced stabilization-destabilization: production of the Arabidopsis thaliana protein APG8a (At4g21980) for NMR," Prot. Exp. Purif. 34, 280-283 (2004).  
     
  T.E. Machonkin, W.M. Westler, J.L. Markley "Novel strategy for the study of paramagnetic proteins with slow electronic relaxation rates by NMR spectroscopy: application to oxidized human [2Fe-2S] ferredoxin," J. Am. Chem. Soc. 126, 5413-5426 (2004).  
     
  O. Y. Dmitriev, F. Abildgaard, J.L. Markley, R.H. Fillingame "Backbone 1H, 15N and 13C assignments for the subunit A of the E. coli ATP synthase," J. Biomol. NMR 29, 439-440 (2004).  
     
  I.Y. Park, M.K. Eidsness, I.-J. Lin, E.B. Gebel, B. Youn, J.L. Harley, T.E. Machonkin, R.O. Frederick, J.L. Markley, E. Smith, T. Ichiye, C.H. Kang "Crystallographic studies on V44 mutants of Clostridium pasteurianum rubredoxin: effects of side chain size on reduction potential," Proteins 57, 618-625 (2004).  
     
  D.A. Vinarov, B.L. Lytle, F.C. Peterson, E.M. Tyler, B.F. Volkman, J.L. Markley "Cell-free protein production and labeling protocol for NMR-based structural proteomics," Nature Methods 1, 149-153 (2004).  
     
  N. Sugimori, T. Torizawa, D.J. Aceti, S. Thao, J.L. Markley, M. Kainosho "Letter to the Editor: 1H, 13C and 15N backbone assignment of a 32kDa hypothetical protein from Arabidopsis thaliana, At3g16450," J. Biomol. NMR 30, 357-358 (2004).  
     
  J.F. Doreleijers, S. Mading, D. Maziuk, K. Sojourner, L. Yin, J. Zhu, J.L. Markley, E.L. Ulrich "BioMagResBank database with sets of experimental NMR constraints corresponding to the stuctures of over 1400 biomolecules deposited in the Protein Data Bank," J. Biomol. NMR 26, 139-146 (2004).  
     
  C.J. Oldfield, E.L. Ulrich, Y.G. Cheng, A.K. Dunker, J.L. Markley "Addressing the intrinsic disorder bottleneck in structural proteomics," Proteins: Struct. Func. Bioinf. 59, 444-453 (2004).  
     
  J. Song, D.A. Vinarov, E.M. Tyler, M.N. Shahan, R.C. Tyler, J.L. Markley "Hypothetical protein At2g24940.1 from Arabidopsis thaliana has a cytochrome B5 like fold," J. Biomol. NMR 30, 215-218 (2004).  
     
     
  2003  
     
  Z. Zolnai, P.T. Lee, J. Li, M.R. Chapman, C.S. Newman, G.N. Phillips, Jr., I. Rayment, E.L. Ulrich, B.F. Volkman, and J.L. Markley, "Project Managment System for Structural and Functional Proteomics: Sesame," J. Structural and Functional Genomics 4, 11-23 (2003).  
     
  F.A.J. Rotsaert, J.D. Pikus, B.G. Fox, J.L. Markley, J. Sanders-Loehr, "N-Isotope Effects on the Raman Spectra of Fe2S2 Ferredoxins and Rieske Ferredoxins: Evidence for Structural Rigidity of Metal Sites," J. Biol. Inorg. Chem. 8, 318-326 (2003).  
     
  J. Song, M. Laskowski, Jr., M.A. Qasim, and J.L. Markley, "NMR Determination of pKa Values for Asp, Glu, His, and Lys Mutants at Each Variable Contiguous Enzyme - Inhibitor Contact Position of Turkey Ovomucoid Third Domain," Biochemistry 42, 2847-2856 (2003).  
     
  I.-J. Lin, E.B. Gebel, T.E. Machonkin, W.M. Westler, and J.L. Markley, "Correlation Between Hydrogen Bond Lengths and Reduction Potentials in Clostridium pasteurianum Rubredoxin," J. Am. Chem. Soc. 125, 1464-1465 (2003).  
     
  J.F. Doreleijers, S. Mading, d. Maziuk, K. Sojourner, L. Yin, J. Zhu, J.L. Markley, and E.L. Ulrich, "BioMagResBank database with sets of experimental NMR constraints corresponding to the structures of over 1400 biomolecules deposited in the Protein Data Bank," J. Biomolecular NMR 26, 139-146 (2003).  
     
  J. Song and J.L. Markley, "Protein Inhibitors of Serine Proteinases: Role of Backbone Structure and Dynamics in Controlling the Hydrolysis Constant," Biochemistry 42, 5186-5194 (2003).  
     
  J. Song, M. Laskowski, Jr., M.A. Qasim, and J.L. Markley, "Two Conformational States of Turkey Ovomucoid Populted at Low pH: Three-Dimensional Structures, Internal Dynamics, and Interconversion Kinetics and Thermodynamics," Biochemistry 42, 6380-6391 (2003).  
     
  F.M. Assadi-Porter, F. Abildgaard, H. Blad, and J.L. Markley, "Correlation of the Sweetness of Variants of the Protein Brazzein with Patterns of Hydrogen Bonds Detected by NMR Spectroscopy," J. Biol. Chem. 278, 32331-31339 (2003).  
     
  Z. Jin, V. Danilova, F.M. Assadi-Porter, D.J. Aceti, J.L. Markley, and G. Hellekant, "Critical Regions for the Sweet Taste of Brazzein," FEBS Lett. 544, 33-37 (2003).  
     
  W-.J. Wu, G. Vidugiris, E.S. Mooberry, W.M. Westler, J.L. Markley, "Mixing Apparatus for Preparing NMR Samples Under Pressure," J. Magn. Reson. 164, 84-91 (2003).  
     
  J.L. Markley, E.L. Ulrich, W.M. Westler, and B.F. Volkman, "Macromolecular Structure Determination by NMR Spectroscopy," Methods Biochem. Anal. 44, 89-113 (2003).  
     
  Z. Jin, V. Danilova, F.M. Assadi-Porter, J.L. Markley, and G. Hellekant, "Monkey Electrophysiological and Human Psychophysical Responses to Mutants of the Sweet Protein Brazzein: Delineating Brazzein Sweetness," Chemical Senses 28, 491-498 (2003).  
     
  Q. Zhao, R. Frederick, K. Seder, S. Thao, H. Sreenath, F. Peterson, B.F. Volkman, J.L. Markley, and B.G. Fox, "Production in Two-Liter Beverage Bottles of Proteins for NMR Structure Determination Labeled with Either 15N- or 13C,15N," J. Struct. Funct. Genomics, in press (2003).  
     
  Y. K. Chae, H. Im, Q. Zhao, J. H. Doelling, R. D. Vierstra, and J. L. Markley, "Prevention of Aggregation after Refolding by Balanced Stabilization-Destabilization: Production of the Arabidopsis thaliana Protein At4g21980 (APG8a) for NMR Structure Determination" Protein Prod. Purif., in press (2003).  
     
     
  2002  
     
  W.F. Walkenhorst, J.A. Edwards, J.L. Markley, and H. Roder, "Early formation of a beta hairpin during folding of staphylococcal nuclease H124L as detected by pulsed hydrogen exchange," Protein Science 11, 82-91 (2002).  
     
  M. L. DeRider, S. J. Wilkens, M. J. Waddell, L. E. Bretscher, F. Weinhold, R. T. Raines, and J. L. Markley "Collagen Stability: Insights from NMR Spectroscopic and Hybrid Density Functional Computational Investigations of the Effect of Electronegative Substituents on Prolyl Ring Conformation," J Am Chem Soc 124, 2497-2505 (2002).  
     
  T. E. Machonkin, W. M. Westler, and J. L. Markley, "13C{13C} 2D NMR: a Novel Strategy for the Study of Paramagnetic Proteins with Slow Electronic Relaxation Rates," J. Am. Chem. Soc. 124, 3204-3205 (2002).  
     
  J. L. Markley, E. L. Ulrich, W. M. Westler, and B. F. Volkman, "Macromolecular Structure Determination by NMR," In Structural Bioinformatics (H. Weissig, and P. Bourne,eds.), Wiley and Sons, New York, (2002).  
     
  S. J. Wilkens, W. Westler, F. Weinhold, and J. L. Markley, "Trans-Hydrogen-Bond h2JNN and h1JNH Couplings in the DNA A-T Base Pair: Natural Bond Orbital Analysis," J. Am. Chem. Soc. 124, 1190-1191 (2002).  
     
  T. E. Machonkin and J. L. Markley, Electron-Nuclear Interactions in Iron-Sulfur Proteins, In Encyclopedia of Nuclear Magnetic Resonance: Supplementary Volume, (D. M. Grant and R. K. Harris, eds), John Wiley & Sons, Ltd, New York, pp. 384-401, 2002.  
     
  W. M. Westler, P. A. Frey, J. Lin, D. Wemmer, P. G. Williams, and J. L. Markley, "Evidence for a Strong Hydrogen Bond in the Catalytic Dyad of Transition State Analog Inhibitor Complexes of Chymotrypsin from Proton-Triton NMR Chemical Shift Differences," J. Am. Chem. Soc. 124, 4196-4197 (2002).  
     
  O. Y. Dmitriev, F. Abildgaard, J. L. Markley, and R. H. Fillingame, "Structure of Ala24/Asp61?Asp24/Asn61 Substituted Subunit c of Escherichia coli ATP Synthase: Implications for the Mechanism of Proton Transport and Rotary Movement in the Fo Complex," Biochemistry 41, 5537-5547 (2002).  
     
  E. S. Kuloglu, D. R. McCaslin, J. L. Markley, and B. F. Volkman, "Structural rearrangement of human lymphotactin, a C chemokine, under physiological solution conditions," J. Biol. Chem. 277, 17863-17870 (2002).  
     
  R. Fogh, J. Ionides, E. Ulrich, W. Boucher, W. Vranken, J. P. Linge, Habeck, M., W. Rieping, T. N. Bhat, J. Westbrook, K. Henrick, G. Gilliland, H. Berman, J. Thornton, M. Nilges, J. Markley, and E. Laue, "The CCPN project: an interim report on a data model for the NMR community," Nature Struct. Biol. 9, 416-418 (2002).  
     
  B. J. Goodfellow, S. G. Nunes, F. Rusnak, I. Moura, C. Ascenso, J. J. G. Moura, B. F. Volkman, and J. L. Markley, "Pseudocontact shifts in Desulfovibrio gigas desulforedoxin", Protein Sci. 11 2464-2470 (2002).  
     
  Q. Zhao, Y. K. Chae, and J. L. Markley "NMR Solution Structure of ATTp - an Arabidopsis thaliana Trypsin Inhibitor," Biochemistry, 41 12284-12296 (2002).  
     
  M. A. Kennedy, G. T. Montelione, C. H. Arrowsmith, and J. L. Markley, "A Role for NMR in Structural Genomics," Journal of Structural and Functional Genomics, 2 11-23 (2002).  
     
  W. M Westler, F. Weinhold, and J. L. Markley, "Quantum Chemical Calculations on Structural Models of the Catalytic Site of Chymotrypsin: Comparison of Calculated Results with Experimental Data from NMR Spectroscopy," J. Am. Chem. Soc. 124 , 14373-14381 (2002).  
     
     
  2001  
     
  D. Chen, A.L. Zangl, Q. Zhao, J.L. Markley, J. Zheng, I.M. Bird, R.R. Magness, "Ovine caveolin-1: cDNA cloning, E. coli expression, and association with endothelial nitric oxide synthase ," Mol Cell Endocrinol 175, 41-56 (2001).
 
     
  H.Hemmi, J.M. Studts, Y.K. Chae, J, Song, J.L. Markley, and B.G. Fox, "Solution structure of the toluene 4-monooxygenase effector protein (T4moD) ," Biochemistry 40, 3512-3524 (2001).  
     
  J. Song, and J.L. Markley, "NMR chemical shift mapping of the binding site of a protein proteinase inhibitor: changes in the (1)H, (13)C and (15)N NMR chemical shifts of turkey ovomucoid third domain upon binding to bovine chymotrypsin A(alpha)," J Mol Recognit 14, 166-171 (2001).  
     
  S. J. Wilkens, W. M. Westler, J. L. Markley, and F. Weinhold, "Natural J-Coupling Analysis: Interpretation of Scalar J-Couplings in Terms of Natural Bond Orbitals," J Am Chem Soc 123, 12026-12036 (2001).  
     
  E. S. Kuloglu, D. R. McCaslin, M. Kitabwalla, C. D. Pauza, J. L., Markley, and B. F. Volkman, "Monomeric Solution Structure for the Prototypical ‘C’ Chemokine Lymphotactin," Biochemistry 40, 12486-12496 (2001).  
     
  W. Luo, L. A. Moe, L. Skjeldal, J. D. Pikus, F. Abildgaard, J. L. Markley, and B. G. Fox, "Assignment of 1H, 13C and 15N NMR signals from toluene 4-monooxygenase Rieske ferredoxin in its oxidized state," J Biomol NMR 21, 73-74 (2001).  
     
     
  2000  
     
  F.M. Assadi-Porter, D.J. Aceti, H. Cheng, and J.L. Markley, "Efficient production of recombinant brazzein, a small, heat-stable, sweet-tasting protein of plant origin ," Arch. Biochem. Biophys. 376, 252-258 (2000).  
     
  F.M. Assadi-Porter, D.J. Aceti, and J.L. Markley , "Sweetness determinant sites of brazzein, a small, heat-stable, sweet-tasting protein ," Arch Biochem Biophys 376, 259-265 (2000).  
     
  H.Hemmi, J.M. Studts, Y.K. Chae, J.L. Markley, and B.G. Fox, "Assignment of 1H, 13C and 15N NMR signals in the toluene 4-monooxygenase effector protein ," J. Biomol NMR 16, 359-360 (2000).  
     
  Y.Kee Chae, and J.L. Markley, "Functional recombinant rabbit muscle phosphoglucomutase from Escherichia coli ," Protein Expr Purif 20, 124-127 (2000).  
     
  B. Xia, D. Jenk, D.M. LeMaster, W.M. Westler, and J.L. Markley, "Electron-nuclear interactions in two prototypical 2Fe-2S proteins: selective (chiral) deuteration and analysis of (1)H and (2)H NMR signals from the alpha and beta hydrogens of cysteinyl residues that ligate the iron in the active sites of human ferredoxin and Anabaena 7120 vegetative ferredoxin ," Arch Biochem Biophys 373, 328-334 (2000).  
     
     
  1999  
     
  J.E. Caldwell and J.L. Markley, "Structure-Function Relationships in Sweet-Tasting Proteins," J Chem Soc Pakistan 21, 268-280 (1999).  
     
  Y.K. Chae, F. Abildgaard, C.A., Royer and J.L. Markley, "Oligomerization of the EK18 mutant of the trp repressor of Escherichia coli as observed by NMR spectroscopy ," Arch Biochem Biophys 371, 35-40 (1999).  
     
  R.W. Curley, Jr., A.K. Sundaram, J.W. Fowble, F. Abildgaard, W.M. Westler, and J.L. Markley, "NMR Studies of Retinoid-Protein Interactions: The Conformation of [13-C]-beta-Ionones Bound to beta-Lactoglobin B," Pharmaceutical Research 16, 651-659 (1999).  
     
  G. Kaslik, W.M. Westler, L. Graf, and J.L. Markley, "Properties of the His57 - Asp102 Dyad of Rat Trypsin D189S in the Zymogen, Activated Enzyme, and alpha1-Proteinase Inhibitor Complexed Forms," Arch. Biochem. Biophys. 362, 254-264 (1999).  
     
  M.A. Qasim, S.M. Lu, J. Ding, K.S. Bateman, M.N.G. James, S. Anderson, J. Song, J.L. Markley, P.J. Ganz, C.W. Saunders, and M. Laskowski, Jr., "Thermodynamic Criterion for the Conformation of P1 Residues of Substrates and of Inhibitors in Complexes with Serine Proteinases," Biochemistry 38, 7142-7150 (1999).  
     
  J. Schleucher, P. Vanderveer, J.L. Markley, and T.D. Sharkey, "Intramolecular Deuterium Distribution of Glucose Reveals Metabolic Regulation and Explains Hydrogen Isotope Ratios," Plant, Cell and Environment 22, 525-533 (1999).  
     
  B.F. Volkman, M.E. Anderson, K.D. Clark, Y. Hoyakawa, M.R. Strand, and J.L. Markley, "Structure of the Insect Cytokine Peptide Plasmatocyte-Spreading Peptide 1 from Pseudoplusia includens," J. Biol. Chem. 274, 4493-4496 (1999).  
     
  B.F. Volkman, S.J. Wilkens, A.L. Lee, B. Xia, W.W. Westler, R. Beger, and J.L. Markley, "Redox-Dependent Magnetic Alignment of Clostridium pasteurianum Rubredoxin: Measurement of Magnetic Susceptibility Anisotropy and Prediction of Pseudocontact Shift Contributions," J. Am. Chem. Soc. 121, 4677-4683 (1999).  
     
  B. Xia, J.D. Pikus, W. Xia, K. McClay, R.J. Steffan, Y.K. Chae, W.M. Westler, J.L. Markley, and B.G. Fox, "Detection and Classification of Hyperfine-Shifted 1-H, 2-H, and 15-N Resonances of the Rieske Ferredoxin Component of Toluene 4-Monooxygenase," Biochemistry 38, 727-39 (1999).  
     
     
  1998  
     
  S.L. Alam, B.F. Volkman, J.L. Markley, and J.D. Satterlee, "Detailed NMR Analysis of the Heme-Protein Interactions in Component IV-Glycera dibranchiata Monomeric Hemoglobin-CO," J. Biomol. NMR 11, 119-133 (1998).  
     
  J.E. Caldwell, F. Abildgaard, D. Ming, G. Hellekant, and J.L. Markley, "Complete 1-H and Partial 13-C Resonance Assignments at 37 and 22 ?C for Brazzein, an Intensely Sweet Protein," J. Biomol. NMR 11, 231-232 (1998).  
     
  J.E. Caldwell, F. Abildgaard, Z. Dzakula, D. Ming, G. Hellekant, and J.L. Markley, "Solution structure of the Thermostable Sweet-Tasting Protein Brazzein," Nature Structural Biology 5, 427-431 (1998).  
     
  Y.K. Chae, F. Abildgaard, E.R. Chapman, and J.L. Markley, "Lipid Binding Ridge on Loops 2 and 3 of the C2A Domain of Synaptotagmin I as Revealed by NMR Spectroscopy," J. Biol. Chem. 273, 25659-25663 (1998).  
     
  S. Choe, Z. Dzakula, J.L. Markley, "Assignment of 1-H, 13-C, and 15-N Signals of Turkey Ovomucoid Third Domain at pH 2.0," J. Biomol. NMR 12, 193-195 (1998).  
     
  R. Chylla, B.F. Volkman, and J.L. Markley, "Practical Model Fitting Approaches to the Direct Extraction of NMR Parameters Simultaneously from All Dimensions of Multidimensional NMR Spectra, J. Biomol. NMR 12, 277-297 (1998).  
     
  Z. Dzakula, N. Juranic, M.L. DeRider, W.M. Westler, S. Macura, and J.L. Markley, "Analysis of Error Propagation from NMR-Derived Internuclear Distances into Molecular Structure of Cyclo-Pro-Gly," J. Magn. Reson. 135, 454-465 (1998).  
     
  M.E. Girvin, V.K. Rastogi, F. Abildgaard, J.L. Markley, and R.H. Fillingame, "Solution Structure of the Transmembrane H+-Translocating Subunit of the F1F0 ATP Synthase," Biochemistry 37, 8817-8824 (1998).  
     
  M. Hirasawa, J.K. Hurley, Z. Salamon, G. Tollin, J.L. Markley, H. Cheng, B. Xia, and D.B. Knaff, "The Role of Aromatic and Acidic Amino Acids in the Electron Transfer Reaction Catalyzed by Spinach Ferredoxin-Dependent Glutamate Synthase," Biochim. Biophys. Acta 1363, 134-146 (1998).  
     
  J. Lin, W.M. Westler, W.W. Cleland, J.L. Markley, and P.A. Frey, "Fractionation Factors and Activation Energy for Exchange of the Low Barrier Hydrogen Bonding Proton in Peptidyl Trifluoromethyl Ketone Complexes of Chymotrypsin," Proc. Natl. Acad. Sci. U.S.A. 95, 14664-14668 (1998).  
     
  J.L. Markley, A. Bax, Y. Arata, C.W. Hilbers, R. Kaptein, B.D. Sykes, P.E. Wright, and K. Wuthrich, "Recommendations for the Presentation of NMR Structures of Proteins and Nucleic Acids," Pure and Appl. Chem. 70, 117-142 (1998).  
     
  J.L. Markley, A. Bax, Y. Arata, C.W. Hilbers, R. Kaptein, B.D. Sykes, P.E. Wright, and K. Wuthrich, "Recommendations for the Presentation of NMR Structures of Proteins and Nucleic Acids," J. Biomol. NMR 12, 1-23 (1998).  
     
  J.L. Markley, A. Bax, Y. Arata, C.W. Hilbers, R. Kaptein, B.D. Sykes, P.E. Wright, and K. Wuthrich, "Recommendations for the Presentation of NMR Structures of Proteins and Nucleic Acids," J. Mol. Biol. 280, 933-952 (1998).  
     
  J.L. Markley, A. Bax, Y. Arata, C.W. Hilbers, R. Kaptein, B.D. Sykes, P.E. Wright, and K. Wuthrich, "Recommendations for the Presentation of NMR Structures of Proteins and Nucleic Acids," Eur. J. Biochem. 256, 1-15 (1998).  
     
  K.E. Prehoda, E.S. Mooberry, and J.L. Markley, "High Pressure Effects on Protein Structure," In Protein Dynamics, Function and Design (O. Jardetzky and J.-F. Lefevre, Eds.), NATO ASI Series, Plenum Press, pp. 59-86 (1998).  
     
  K.E. Prehoda, E.S. Mooberry, and J.L. Markley, "Pressure Denaturation of Proteins: Evaluation of Compressibility Effects," Biochemistry 37, 5785-5790 (1998).  
     
  B.F. Volkman, S.L. Alam, J.D. Satterlee, and J.L. Markley, "Solution Structure and Backbone Dynamics of Component IV-Glycera dibranchiata Monomeric Hemoglobin-CO," Biochemistry 37, 10906-10919 (1998).  
     
  L. Wang, Y. Li, F. Abildgaard, J.L. Markley, and H. Yan, "NMR Solution Structure of Type II Human Cellular Retinoic Acid Binding Protein: Implications for Ligand Binding," Biochemistry 37, 12727-12736 (1998).  
     
  A.M. Weber-Main, J.K., Hurley, H. Cheng, B. Xia, Y.K. Chae, J.L. Markley, M. Martinez Julvez, C. Gomez-Moreno, M. T. Stankovich, and G. Tollin, "An Electrochemical, Kinetic, and Spectroscopic Characterization of [2Fe-2S] Vegetative and Heterocyst Ferredoxins from Anabaena 7120 with Mutations in the Cluster Loop," Arch. Biochem. Biophys. 355, 181-188 (1998).  
     
  S.J. Wilkens, B. Xia, B.F. Volkman, F. Weinhold, J.L. Markley, and W.M. Westler, "Inadequacies of the Point-Dipole Approximation for Describing Electron-Nuclear Interactions in Paramagnetic Proteins: Hybrid Density Functional Calculations and the Analysis of NMR Relaxation of High-Spin Fe(III) Rubredoxin," J. Phys. Chem. 102, 8300-8305 (1998).  
     
  S.J. Wilkens, B. Xia, F. Weinhold, J.L. Markley, and W.M. Westler, "NMR Investigations of Clostridium pasteurianum Rubredoxin. Origin of Hyperfine 1-H, 2-H, 13-C, and 15-N NMR Chemical Shifts in Iron-Sulfur Proteins: Comparison of Hybrid Density Functional Calculations with Experimental Data," J. Am. Chem. Soc. 120, 4806-4814 (1998).  
     
  B. Xia, B.F. Volkman, and J.L. Markley, "Evidence for Oxidation-State-Dependent Conformational Changes in Human Ferredoxin from Multinuclear, Multidimensional NMR Spectroscopy," Biochemistry 37, 3965-3973 (1998).  
     
  B. Xia, S.J. Wilkens, W.M. Westler, and J.L. Markley, "Amplification of One-Bond 1-H/2-H Isotope Effects on 15-N Chemical Shifts in Clostridium pasteurianum Rubredoxin by Fermi-Contact Effects through Hydrogen Bonds," J. Am. Chem. Soc. 120, 4893-4894 (1998).  
     
     
  1997  
     
  Z. An, Q, Zhao, J. McEvoy, W.M. Yuan, J.L. Markley, and S.A. Leong, "The Second Finger of Urbs1 is Required for Iron-Mediated Repression of sid1 in Ustilago maydis," Proc. Natl. Acad. Sci. USA 94, 5882-5887 (1997).
 
     
  P.T. Chivers, K.E. Prehoda, B.F. Volkman, B.-M. Kim, J.L. Markley, and R.T. Raines, "Microscopic pK(a) Values of Escherichia coli Thioredoxin," Biochemistry 36, 14985-14991 (1997).  
     
  J. K. Hurley, A.M. Weber-Main, M.T. Stankovich, M.M. Benning, J.B. Thoden, J.L. Vanhooke, H.M. Holden, Y.K. Chae, B. Xia, H. Cheng, J.L. Markley, M. Martinez-Julvez, C. Gomez-Moreno, J.L. Schmeits, and G. Tollin, "Structure-Function Relationships in Anabaena Ferredoxin: Correlations Between X-ray Crystal Structures, Reduction Potentials, and Rate Constants of Electron Transfer to Ferredoxin:NADP+ Reductase for Site-Specific Ferredoxin Mutants," Biochemistry 36, 11100-11117 (1997).
 
     
  J.K. Hurley, A.M. Weber-Main, A.E. Hodges, M.T. Stankovich, M.M. Benning, H.M. Holden, H. Cheng, B. Xia, J.L. Markley, C. Genzor, C. Gomez-Moreno, R. Hafezi, and G. Tollin, "Iron-Sulfur Cluster Cysteine-to-Serine Mutants of Anabaena [2Fe-2S] Ferredoxin Exhibit Unexpected Redox Properties and are Competent in Electron Transfer to Ferredoxin:NADP+ Reductase," Biochemistry 36, 15109-15117 (1997).  
     
  G. Kaslik, J. Kardos, E. Szabo, L. Szilagyi, P. Zavodszky, W.M. Westler, J.L. Markley, and L. Graf, "Effects of Serpin Binding on the Target Proteinase: Global Stabilization, Localized Increased Structural Flexibility, and Conserved Hydrogen Bonding at the Active Site," Biochemistry 29, 5455-5464 (1997).
 
     
  A.M. Prantner, B.F. Volkman, S.J. Wilkens, B. Xia, and J.L. Markley, "Assignment of 1-H, 13-C, and 15-N Signals of Reduced Clostridium pasteurianum Rubredoxin: Oxidation State-Dependent Changes in Chemical Shifts and Relaxation Rates," J. Biomol. NMR 10, 411-412 (1997).  
     
  H. Remigy, M. Jaquinod, Y. Pétillot, J. Gagnon, H. Cheng, B. Xia, J.L. Markley, J. K. Hurley, G. Tollin, and E. Forest, "Probing the Influence of Mutations on the Stability of a Ferredoxin by Mass Spectrometry," J. Protein Chem. 16, 527-532 (1997).
 
     
  B.F. Volkman, A.M. Prantner, S.J. Wilkens, B. Xia, and J.L. Markley, "Assignment of 1-H, 13-C, and 15-N Signals of Oxidized Clostridium pasteurianum Rubredoxin," J. Biomol. NMR 10, 409-410 (1997).  
     
  J. Wang, D.M. Truckses, F. Abildgaard, Z. Dzakula, Z. Zolnai, and J.L. Markley, "Solution Structures of Staphylococcal Nuclease from Multinuclear NMR: Nuclease H124L and its Ternary Complex with Ca(2+) and Thymidine-3',5'-Bisphosphate," J. Biomol. NMR 10, 143-164 (1997).
 
     
     
  1996  
     
  Z. Dzakula, M.L. DeRider, and J.L. Markley, "Conformational Analysis of Molecules with Five-Membered Rings through NMR Determination of the Continuous Probability Distribution (CUPID) for Pseudorotation," J. Am. Chem. Soc. 118, 12796-12803 (1996).  
     
  Z. Dzakula, W.M. Westler, and J.L. Markley, "Continuous Probability Distribution (CUPID) Analysis of Potentials for Internal Rotations," J. Magn. Reson. Ser. B 111, 109-126 (1996).
 
     
  A.P. Hinck, D.M. Truckses, and J.L. Markley, "Engineered Disulfide Bonds in Staphylococcal Nuclease: Effects on Conformational Forms and Stability of the Folded Protein," Biochemistry 35, 10328-10338 (1996).  
     
  A.P. Hinck, W.F. Walkenhorst, D.M. Truckses, and J.L. Markley, "NMR and Mutagenesis Investigations of a Model Cis:Trans Peptide Isomerization Reaction: Xaa-116-Pro-117 of Staphylococcal Nuclease and its Role in Protein Folding and Stability," In Biological NMR Spectroscopy (J.L. Markley and S. J. Opella, Eds.), Oxford University Press, 133-160 (1996).  
     
  C.B. Hoogstraten and J.L. Markley, "Approaches to the Determination of More Accurate Cross-Relaxation Rates and the Effects of Improved Distance Constraints on Protein Solution Structures," In Dynamics and the Problem of Recognition in Biological Macromolecules (O. Jardetzky and J.-F. Lefevre, Eds.), Plenum Press, pp. 73-111 (1996).
 
     
  C.G. Hoogstraten and J.L. Markley, "Effects of Experimentally Achievable Improvements in the Quality of NMR Distance Constraints on the Accuracy of Calculated Protein Structures," J. Mol. Biol. 258, 334-348 (1996).
 
     
  J.L. Markley and S.J. Opella, Eds., Biological NMR Spectroscopy, Oxford University Press, New York, 1996.
 
     
  J.L. Markley, C.A. Royer, and D. Northrop, Eds., High-Pressure Effects in Molecular Biophysics and Enzymology, Oxford University Press, New York, 1996.  
     
  J.L. Markley and W.M. Westler, "Protonation-State Dependence of Hydrogen Bond Strengths in a Serine Protease Catalytic Triad: Bovine Chymotrypsinogen A," Biochemistry 35, 11092-11097 (1996).
 
     
  J.L. Markley, B. Xia, Y. K. Chae, H. Cheng, W.M. Westler, J.D. Pikus, and B.G. Fox, "NMR Approaches to the Study of Structure-Function Relationships in Iron-Sulfur Proteins: Rubredoxin, [2Fe-2S] Ferredoxins, and a Rieske Protein," In Protein Structure Function Relationship (Z. Zaidi and D. Smith, Eds.), Plenum Press, London, pp. 135-146 (1996).
 
     
  K.E. Prehoda, S.N. Loh, and J.L. Markley, "Modeling Volume Changes in Proteins using Partial Molar Volumes of Model Compounds," In Techniques in Protein Chemistry VII (D.R. Marshak, Ed.), Academic Press, New York, pp 433-438 (1996).  
     
  K.E. Prehoda and J.L. Markley, "Use of Partial Molar Volumes of Model Compounds in the Interpretation of High-Pressure Effects on Proteins," In High-Pressure Effects in Molecular Biophysics and Enzymology (J.L. Markley, C. A. Royer, and D. Northrop, Eds.), Oxford University Press, pp. 33-43 (1996).  
     
  D.M. Truckses, R.R. Somoza, K.E. Prehoda, and J.L. Markley, "Coupling between cis/trans Proline Isomerization and Protein Stability in Staphylococcal Nuclease," Protein Sci. 5, 1907-1916 (1996).  
     
  G.A.J. Vidugiris, D.M. Truckses, J.L. Markley, and C.A. Royer, "High-Pressure Denaturation of Staphylococcal Nuclease Proline to Glycine Substitution Mutants," Biochemistry 35, 3857-3864 (1996).  
     
  B. Xia, H. Cheng, V. Bandarian, G.H. Reed, and J.L. Markley, "Human Ferredoxin: Overproduction in Escherichia coli, Reconstitution in vitro, and Spectroscopic Studies of Iron-Sulfur Cluster Ligand Cysteine-to-Serine Mutants," Biochemistry 35, 9488-9495 (1996).  
     
  B. Xia, H. Cheng, Y.K. Chae, L. Skjeldal, W.M. Westler, and J.L. Markley, "Iron-Sulfur Proteins: Investigations of Hyperfine-Shifted Hydrogen, Carbon, and Nitrogen Resonances," In NMR as a Structural Tool For Macromolecules: Current Status and Future Directions (B. D. Nageswara Rao and M. D. Kemple, Eds.), Plenum Press, pp. 251-274 (1996).
 
     
  Z. Zolnai, N. Juranic, J.L. Markley, and S. Macura, "Zooming: a Practical Strategy for Improving the Quality of Multidimensional NMR Spectra," J. Magn. Reson. Ser. A. 119, 53-64 (1996).  
     
     
  1995  
     
  B.M. Burkhart, B. Ramakrishnan, H. Yan, R.J. Reedstrom, J.L. Markley, N.A. Straus, and M. Sundaralingam, "Molecular Structure of the Trigonal Form of Recombinant Oxidized Flavodoxin from Anabaena 7120 at 1.40 A Resolution," Acta. Crystallogr. Ser. D. 51, 318-330 (1995).  
     
  Y.K. Chae and J.L. Markley, "Analysis of the Hyperfine-Shifted Nitrogen-15 Resonances of the Oxidized Form of Anabaena 7120 Heterocyst Ferredoxin," Biochemistry 34, 188-193 (1995).  
     
  Y.K. Chae and J.L. Markley, "Mutagenesis Studies of Anabaena 7120 [2Fe-2S] Ferredoxins: Physical and Chemical Characteristics of Hybrid Vegetative/Heterocyst Sequences," In Photosynthesis: from Light to Biosphere (P. Mathis, Ed.), Kluwer Academic Publishers, Vol. II, 633-638 (1995).
 
     
  Y.K. Chae, B. Xia, H. Cheng, B.-H. Oh, L. Skjeldal, W.M. Westler, and J.L. Markley, "Multinuclear Magnetic Resonance and Mutagenesis Studies of Structure-Function Relationships in [2Fe-2S] Ferredoxins," In Nuclear Magnetic Resonance of Paramagnetic Proteins (G. N., LaMar, Ed.), Nato ASI Series C, Vol. 457, Kluwer, Dordrecht, pp 297-317 (1995).  
     
  H. Cheng and J.L. Markley, "NMR Spectroscopic Studies of Paramagnetic Proteins: Iron-Sulfur Proteins," Ann. Rev. Biophys. Biomol. Structure 24, 209-237 (1995).  
     
  H. Cheng, W.M. Westler, B. Xia, B.-H. Oh, and J.L. Markley, "Protein Expression, Selective Isotopic Labeling, and Analysis of Hyperfine-Shifted NMR Signals of Anabaena 7120 Vegetative [2Fe-2S] Ferredoxin," Arch. Biochem. Biophys 316, 619-634 (1995).
 
     
  R.A. Chylla and J.L. Markley, "Theory and Application of the Maximum Likelihood Principle to NMR Parameter Estimation of Multidimensional NMR Data," J. Biomol. NMR 5, 245-258 (1995).  
     
  A.S. Edison, J.L. Markley, and F. Weinhold, "Ab Initio Calculations of Protium/Deuterium Fractionation Factors in O2H5+ Clusters," J. Phys. Chem. 99, 8013-8016 (1995).
 
     
  A.S. Edison, F. Weinhold, and J.L. Markley, "Theoretical Studies of Protium/Deuterium Fractionation Factors and Cooperative Hydrogen Bonding in Peptides," J. Am. Chem. Soc. 117, 9619-9624 (1995).  
     
  C.G. Hoogstraten, S. Choe, W.M. Westler, and J.L. Markley, "Comparison of the Accuracy of Protein Solution Structures Derived from Conventional and Network-Edited NOESY Data," Protein Science 4, 2289-2299 (1995).
 
     
  C.G. Hoogstraten, W.M. Westler, S. Macura, and J.L. Markley, "NOE Measurements in the Absence of Spin Diffusion: Application to Methylene Groups in Proteins and Effects on Local Structural Parameters," J. Am. Chem. Soc. 117, 5610-5611 (1995); correction, loc. cit. p. 8885.
 
     
  C.G. Hoogstraten, W.M. Westler, E.S. Mooberry, S. Macura, and J.L. Markley, "Analysis of Transverse Cross Relaxation in Proteins within a Simplified Relaxation Submatrix: BD-ROESY," J. Magn. Reson. Ser. B 109, 76-79 (1995).
 
     
  J.K. Hurley, M.S. Caffrey, J.L. Markley, H. Cheng, B. Xia, Y.K. Chae, H.M. Holden, and G. Tollin, "Mutations of Surface Residues in Anabaena Vegetative and Heterocyst Ferredoxin that Affect Thermodynamic Stability as Determined by Guanidine Hydrochloride Denaturation," Protein Sci. 4, 58-64 (1995).  
     
  D. Ming, J.L. Markley, and G. Hellekant, "Quantifying Sulfhydryl Groups of Cysteinyl Residues in Peptides and Proteins," BioTechniques 18, 808-810 (1995).  
     
  J.A. Navarro, M. Hervas, C. Genzor, G. Cheddar, M.F. Fillat, M.A. de la Rosa, C. Gomez-Moreno, H. Cheng, B. Xia, Y.K. Chae, H. Yan, B. Wong, N. Straus, J.L. Markley, J.K. Hurley, and G. Tollin, "Site-Specific Mutagenesis Demonstrates that the Structural Requirements for Efficient Electron Transfer in Anabaena Ferredoxin and Flavodoxin are Highly Dependent on the Reaction Partner: Kinetic Studies with Photosystem I, Ferredoxin:NADP+ Reductase and Cytochrome c," Arch. Biochem. Biophys. 321, 229-238 (1995).  
     
  J.B. Pearson, J.-F. Wang, J.L. Markley, H.-b. Le, and E. Oldfield, "Protein Structure Refinement Using Carbon-13 Nuclear Magnetic Resonance Spectroscopic Chemical Shifts and Quantum Chemistry," J. Am. Chem. Soc. 117, 8823-8829 (1995).
 
     
  T.C. Pinkerton, W. Jeffrey-Howe, E.L. Ulrich, J. P. Comiskey, J. Haginaka, T. Murashima, W.F. Walkenhorst, W.M. Westler, and J.L. Markley, "Protein Binding Chiral Discrimination of HPLC Stationary Phases made with Whole, Fragmented, and Third Domain Turkey Ovomucoid," Anal. Chem. 67, 2354-2367 (1995).  
     
  J. Schleucher, J.L. Markley, and T.D. Sharkey, "Hydrogen Isotope Ratios of Plant Metabolites," In Photosynthesis: from Light to Biosphere (P. Mathis, Ed.), Kluwer Academic Publishers, Vol. V, 1009-1012 (1995).  
     
  G.J.A. Vidugiris. J.L. Markley, and C.A. Royer, "Evidence for a Molten Globule-Like Transition State in Protein Folding from Determination of Activation Volumes," Biochemistry 34, 4909-4912 (1995).  
     
  D.S. Wishart, C.G. Bigam, J. Yao, F. Abildgaard, H. J. Dyson, E. Oldfield, J.L. Markley, and B.D. Sykes, "13-C and 15-N Chemical Shift Referencing in Biomolecular NMR," J. Biomol. NMR 6, 135-140 (1995).  
     
  B. Xia, H. Cheng, L. Skjeldal, V.M. Coghlin, L.E. Vickery, and J.L. Markley, "Multinuclear Magnetic Resonance and Mutagenesis Studies of the Histidine Residues of Human Mitochondrial Ferredoxin," Biochemistry 34, 180-187 (1995).
 
     
  B. Xia, W.M. Westler, H. Cheng, J. Meyer, J.-M. Moulis, and J.L. Markley, "Detection and Classification of Hyperfine-shifted 1-H, 2-H, and 15-N Resonances from the Four Cysteines that Ligate Iron in Oxidized and Reduced Clostridium pasteurianum Rubredoxin," J. Am. Chem. Soc. 117, 5347-5350 (1995).  
     
  H. Zhao, W.M. Westler and J.L. Markley, "Precise Determination of T1 Relaxation Values by a Method in which Pairs of Non-Equilibrium Magnetizations are Measured across a Constant Relaxation Period," J. Magn. Reson. Ser. A 112, 139-143 (1995).
 
     
  Z. Zolnai, N. Juranic, J.L. Markley, and S. Macura, "Magnetization Exchange Network Editing: Mathematical Principles and Experimental Demonstration," Chem. Phys. 200, 161-179 (1995).  
     
     
  1994  
     
  Y.K. Chae, F. Abildgaard, E.S. Mooberry, and J.L. Markley, "Multinuclear, Multidimensional NMR Studies of Anabaena 7120 Heterocyst Ferredoxin. Sequence-Specific Resonance Assignments and Secondary Structure of the Oxidized Form in Solution," Biochemistry 33, 3287-3295 (1994).  
     
  H. Cheng, B. Xia, Y.K. Chae, W.M. Westler, and J.L. Markley, "Magnetic Resonance Studies of Isotopically Labeled Paramagnetic Proteins: [2Fe-2S] Ferredoxins," In Stable Isotope Applications in Biomolecular Structure and Mechanisms (J. Trewhella, T. Cross, & C. J. Unkefer, Eds.), Los Alamos National Laboratory, Los Alamos, pp 171-188 (1994).
 
     
  H. Cheng, B. Xia, G.H. Reed, and J.L. Markley, "Optical, EPR, and 1-H NMR Spectroscopy of Serine-Ligated [2Fe-2S] Ferredoxins Produced by Site-Directed Mutagenesis of Cysteine Residues in Recombinant Anabaena 7120 Vegetative Ferredoxin," Biochemistry 33, 3155-3164 (1994).
 
     
  A.S. Edison, F. Abildgaard, W.M. Westler, E.S. Mooberry, and J.L. Markley, "Practical Introduction to the Theory and Implementation of Multinuclear, Multidimensional NMR Experiments," Methods. Enzymol. 239, 3-79 (1994).  
     
  A.S. Edison, J.L. Markley, and F. Weinhold, "Calculations of One-, Two, and Three-Bond Nuclear Spin-Spin Couplings in a Model Peptide and Experimental Correlations with Experimental Data," J. Biomol. NMR 4, 519-542 (1994).  
     
  A.S. Edison, F. Weinhold, W.M. Westler, and J.L. Markley, "Estimates of phi and psi Torsion Angles in Proteins from One-, Two-, and Three-Bond Nuclear Spin-Spin Couplings: Application to Staphylococcal Nuclease," J. Biomol. NMR 4, 543-551 (1994).  
     
  M. Ghassemian, B. Wong, F. Ferreira, J.L. Markley, and N. Straus, "Cloning, Sequencing and Transcriptional Studies of the Genes for Cytochrome c-553 and Plastocyanin from Anabaena sp. PCC 7120," Microbiology 140, 1151-1159 (1994).  
     
  C. Gomez-Moreno, M. Medina, J.K. Hurley, M.A. Cusanovich, J.L. Markley, H. Cheng, B. Xia, Y.K. Chae, and G. Tollin, "Protein Engineering for the Elucidation of the Mechanism of Electron Transfer in Redox Proteins," Biochem. Soc. Trans. 22, 796-800 (1994).  
     
  H.M. Holden, B.L. Jacobson, J.K. Hurley, G. Tollin, B.-H. Oh, L. Skjeldal, Y.K. Chae, H. Cheng, B. Xia, and J.L. Markley, "Structure-Function Studies of [2Fe-2S] Ferredoxins," J. Bioeng. Biomemb. 26, 67-88 (1994).  
     
  J.K. Hurley, Z. Salamon, T.E. Meyer, J. C. Fitch, M. A. Cusanovich, G. Tollin, H. Cheng, B. Xia, Y.K. Chae, J.L. Markley, M. Medina, and C. Gomez-Moreno, "Structure-Function Relationships in Ferredoxin: Site-Directed Mutagenesis and Time-Resolved Absorption Spectroscopy Applied to the Ferredoxin:Ferredoxin NADP+ Reductase Interaction," In Flavins and Flavoproteins 1993 (K. Yagi, Ed.), Walter de Gruyter, Berlin, pp 435-438 (1994).
 
     
  S. Kornguth, M.E. Anderson, J.L. Markley, and A. Shedlovsky, "Near-Microscopic Magnetic Resonance Imaging of the Brains of Phenylalanine Hydroxylase-Deficient Mice, Normal Littermates, and of Normal BALB/c Mice at 9.4 Tesla," Neuroimage 1, 220-229 (1994).  
     
  A.M. Krezel, P. Darba, A.D. Robertson, J. Fejzo, S. Macura, and J.L. Markley, "Solution Structure of Turkey Ovomucoid Third Domain as Determined from Nuclear Magnetic Resonance Data," J. Mol. Biol. 242, 203-214 (1994).
 
     
  S.N. Loh, and J.L. Markley, "Hydrogen Bonding in Proteins as Studied by Amide Hydrogen D/H Fractionation Factors: Application to Staphylococcal Nuclease," Biochemistry 33, 1029-1036 (1994).  
     
  S. Macura, W.M. Westler, and J.L. Markley, "Two-Dimensional Exchange Spectroscopy of Proteins," Methods Enzymol. 239, 106-144 (1994).
 
     
  S.N. Loh, K.E. Prehoda, J. Wang, and J.L. Markley, "Measuring Global and Local Structural Free Energy Changes in Staphylococcal Nuclease by NMR-Observed Hydrogen Exchange," In Techniques in Protein Chemistry V (J. W. Crabb, Ed.), Academic Press, New York, pp 431-438 (1994).  
     
  S. Macura, J. Fejzo, W.M. Westler, and J.L. Markley, "Influence of Slow Internal Motion in Proteins on Cross-Relaxation Rates Determined by Two-Dimensional Exchange Spectroscopy," Bull. Magn. Reson. 16, 73-93 (1994).
 
     
  J.L. Markley, A.P. Hinck, S.N. Loh, K.E. Prehoda, D.M. Truckses, W.F. Walkenhorst, and J. Wang, "Case Study of Protein Structure, Stability, and Function: NMR Investigations of the Proline Residues in Staphylococcal Nuclease," Pure & Appl. Chem. 66, 65-69 (1994).  
     
  E.S. Mooberry, F. Abildgaard, and J.L. Markley, "Modifications of an Older Model NMR Console for the Collection of Multinuclear, Multidimensional Spectral Data," Methods. Enzymol. 239, 247-256 (1994).  
     
  J.B. Olson, Jr., and J.L. Markley, "Evaluation of an Algorithm for the Automated Sequential Assignment of Protein Backbone Resonances: A Demonstration of the Connectivity Tracing Assignment Tools (CONTRAST) Software Package," J. Biomol. NMR 4, 385-410 (1994).
 
     
  W.F. Walkenhorst, A.M. Krezel, G.I. Rhyu, and J.L. Markley, "Solution Structure of Reactive-Site Hydrolyzed Turkey Ovomucoid Third Domain by Nuclear Magnetic Resonance and Distance Geometry Methods," J. Mol. Biol. 242, 215-230 (1994).  
     
     
  1993  
     
  M. E. Anderson, J.L. Markley, Arus, C. and M. C. Chobanian, "Perifusion Loop-Gap Resonator NMR Probe for Aerobic Cell Suspensions," Magn. Reson. Med. 29, 563-566 (1993).  
     
  I.-J.L. Byeon, H. Yan, A.S. Edison, E.S. Mooberry, F. Abildgaard, J.L. Markley, and M.D. Tsai, "Mechanism of Adenylate Kinase. 1-H, 13-C, and 15-N NMR Assignments, Secondary Structure, and Substrate Binding Sites," Biochemistry 32, 12508-12521 (1993).  
     
  M.E. Cabanas, J. Alonso, C. Arus, M.E. Anderson, W.M. Westler, and J.L. Markley, "A Versatile Perifusion System for the NMR Spectroscopy of Bovine Retina. Assignment of Resonances and Effect of Ischemia," Exp Eye Res. 57, 669-678 (1993).
 
     
  R.A. Chylla and J.L. Markley, Simultaneous Base Point Correction and Signal Recognition in Multidimensional NMR Spectra," J. Magn. Reson. Ser. B 102, 148-154 (1993).  
     
  R.A. Chylla, and J.L. Markley, "Improved Frequency Resolution in Constant-Time Experiments by Multidimensional Bayesian Analysis," J. Biomol. NMR 3, 515-533 (1993).  
     
  A.S. Edison, J.L. Markley, and F. Weinhold, "Calculations of Nuclear Spin-Spin Coupling Constants with Ab Initio Molecular Orbital Wavefunctions," J. Phys. Chem. 97, 11657-11665 (1993).  
     
  D. D. Gilboe, D. Kintner, M. E. Anderson, J. H. Fitzpatrick, S. E. Emoto, and J.L. Markley, "Inorganic Phosphate Compartmentation in the Normal Isolated Canine Brain," J. Neurochem. 60, 2192-2203 (1993).  
     
  J. Haginaka, T. Murashima, T.C., Pinkerton, J.P. Comiskey, E.L. Ulrich, J.L. Markley, and W.F. Walkenhorst, "Enantioselectivity of Ovomucoid Bonded-Phase HPLC Columns Produced with Isolated Domains," Kuromatogurafi 14, 100-101 (1993).  
     
  A.P. Hinck, E.S. Eberhardt, and J.L. Markley, "NMR Strategy for Elucidation of Xaa-Pro Peptide Bond Configurations in Proteins: Mutants of Staphylococcal Nuclease with Altered Configuration at Proline-117," Biochemistry 32, 11810-11818 (1993).
 
     
  A. P. Hinck, W. F. Walkenhorst, W.M. Westler, S. Choe, and J.L. Markley, "Overexpression and Purification of Avian Ovomucoid Third Domains in Escherichia coli," Protein Eng. 6, 221-227 (1993).  
     
  C.G. Hoogstraten, W.M. Westler, S. Macura, and J.L. Markley, "Improved Measurement of Longer Proton-Proton Distances in Proteins by Relaxation Network Editing," J. Magn. Reson. Ser. B 102, 232-235 (1993).
 
     
  J.K. Hurley, H. Cheng, B. Xia, J.L. Markley, M. Medina, C. Gomez-Moreno, and G. Tollin, "An Aromatic Amino Acid is Required at Position 65 in Anabaena Ferredoxin for Rapid Electron Transfer to Ferredoxin:NADP+ Reductase," J. Am. Chem. Soc. 115, 11698-11701 (1993).
 
     
  J. K. Hurley, Z. Salamon, T.E. Meyer, J.C. Fitch, M.A. Cusanovich, J.L. Markley, H. Cheng, B. Xia, Y.K. Chae, M. Medina, C. Gomez-Moreno, and G. Tollin, "Amino Acid Residues in Anabaena Ferredoxin Crucial to Interaction with Ferredoxin-NADP+ Reductase: Site-Directed Mutagenesis and Laser Flash Photolysis," Biochemistry 32, 9346-9354 (1993).  
     
  B.L. Jacobson, Y.K. Chae, J.L. Markley, I. Rayment, and H.M. Holden, "Molecular Structure of the Oxidized, Recombinant, Heterocyst [2Fe-2S] Ferredoxin from Anabaena 7120 Determined to 1.7 A Resolution," Biochemistry 32, 6788-6793 (1993).  
     
  S. N. Loh and J.L. Markley, "Measurement of Amide Hydrogen D/H Fractionation Factors in Proteins by NMR Spectroscopy," In Techniques in Protein Chemistry IV, (R. Angeletti, Ed.), Academic Press, New York, pp 517-524 (1993).
 
     
  S.N. Loh, K.E. Prehoda, J. Wang, and J.L. Markley, "Hydrogen Exchange in Unligated and Ligated Staphylococcal Nuclease," Biochemistry 32, 11022-11028 (1993).  
     
  J.L. Markley, A.P. Hinck, S.N. Loh, K.E. Prehoda, D.M. Truckses, W.F. Walkenhorst, and J. Wang, "Case Study of Protein Structure, Stability, and Function: NMR Investigations of the Proline Residues in Staphylococcal Nuclease," In Protein Structure Function Relationship (Z.H. Zaidi, A. Abbasi, and D.L. Smith, Eds.), TWEL Publishers, Karachi-Doncaster-Gaithersburg, pp 193-202 (1993).
 
     
  J.L. Markley and M. Kainosho, "Stable Isotope Labeling and Resonance Assignments in Larger Proteins," In NMR of Biological Macromolecules: A Practical Approach, (G. C. K. Roberts, Ed.), Oxford University Press, Oxford, 1993, pp 101-152.  
     
  D. C. McCain, J. Croxdale, and J.L. Markley, "Spatial Distribution of Chloroplast Water in Acer platanoides Sun and Shade Leaves," Plant Cell and Environment 16, 727-733 (1993).  
     
  C. Royer, A. P. Hinck, S. N. Loh, K. Prehoda, X. Peng, J. Jonas, and J.L. Markley, "Effects of Amino Acid Substitutions on the Pressure Denaturation of Staphylococcal Nuclease as Monitored by Fluorescence and NMR Spectroscopy," Biochemistry 32, 5222-5232 (1993).  
     
     
  1992  
     
  Z. Dzakula, A.S. Edison, W.M. Westler, and J.L. Markley, "Analysis of chi(1) Rotamer Populations from NMR Data by the CUPID Method," J. Am. Chem. Soc. 114, 6200-6207 (1992).  
     
  Z. Dzakula, W.M. Westler, A.S. Edison and J.L. Markley, "The 'CUPID' Method of Calculating the Continuous Probability Distribution of Rotamers from NMR Data," J. Am. Chem. Soc. 114, 6195-6199 (1992).
 
     
  J. Fejzo, W.M. Westler, J.L. Markley, S. Macura, "Complete Elimination of Spin Diffusion from Selected Resonances in Two-Dimensional Cross-Relaxation Spectra of Macromolecules by a Novel Pulse Sequence (SNOESY)," J. Am. Chem. Soc. 114, 1523-1524 (1992).
 
     
  A.L.P. Houseman, B.-H. Oh, M.C. Kennedy, C. Fan, M.M. Werst, H. Beinert, J.L. Markley, and B.M. Hoffman, "14,15-N, 13-C, TFe, 1,2H Q-band ENDOR Study of Fe-S Proteins with Clusters that Have Endogenous Sulfur Ligands," Biochemistry 31, 2073-2080 (1992).
 
     
  B.L. Jacobson, Y.K. Chae, H. Böhme, J.L. Markley, and H.M. Holden, "Crystallization and Preliminary Analysis of Oxidized, Recombinant, Heterocyst [2Fe-2S] Ferredoxin from Anabaena 7120," Arch. Biochem. Biophys. 294, 297-281 (1992).  
     
  S. Kornguth, E. Bersu, M.E. Anderson, and J. Markley, "Correlation of Increased Levels of Class I MHC H-2K(k) in the Placenta of Murine Trisomy 16 Conceptuses with Structural Abnormalities Revealed by Magnetic Resonance Microscopy," Tetralogy 45, 383-391 (1992).
 
     
  S. Macura, J. Fejzo, C. G. Hoogstraten, W.M. Westler, and J.L. Markley, "Topological Editing of Cross-Relaxation Networks," Israel J. Chem. 32, 245-256 (1992).
 
     
  D.C. McCain and J.L. Markley, "In vivo Study of Chloroplast Volume Regulation," Biophys. J. 61, 1207-1212 (1992).  
     
  D. C. McCain and J.L. Markley, "A Nuclear Magnetic Resonance Imaging Technique Designed for Studies of Water in Plant Leaves," J. Struct. Biol. 108, 195-201 (1992).  
     
  E. S. Mooberry, A. S. Edison, F. Abildgaard, J.L. Markley, I.-J. Byeon, and M.-D. Tsai, "Modification of a Bruker AM-600 Spectrometer for Double and Triple Resonance Three- and Four-Dimensional Experiments Illustrated with Chicken Adenylate Kinase Resonance Assignments," In Spectroscopy and Structure of Molecules and Nuclei, N. R. Johnson, W. N. Shelton, and M. El-Sayed, eds., World Scientific, Singapore, pp. 375-380, 1992.
 
     
  S. T. Rao, F. Shaffie, C. Yu, K. A. Satyshur, B. J. Stockman, J.L. Markley, and M. Sundaralingam, "Structure of the Oxidized Long Chain Flavodoxin from Anabaena 7120 at 2 A Resolution," Protein Science 1, 1413-1427 (1992).
 
     
  B.J. Stockman and J.L. Markley, "NMR Analysis of Ligand Binding," Current Opinion Structural Biology 2, 52-56 (1992).  
     
  J. Wang, A. P. Hinck, S. N. Loh, D. M. LeMaster, and J.L. Markley, "Solution Studies of Staphylococcal Nuclease H124L. 2. 1-H, 13-C, and 15-N Chemical Shift Assignments for the Unligated Enzyme and Analysis of Chemical Shift Changes that Accompany Formation of the Nuclease-3',5'-Thymidine Bisphosphate-Calcium Ternary Complex," Biochemistry 31, 921-936 (1992).  
     
  J. Wang, E.S. Mooberry, W. F. Walkenhorst, and J.L. Markley, "Solution Studies of Staphylococcal Nuclease H124L. 1. Backbone 1-H and 15-N Resonances and Secondary Structure of the Unligated Enzyme as Identified by Three-Dimensional NMR Spectroscopy," Biochemistry 31, 911-920 (1992).  
     
     
  1991  
     
  A.S. Edison, W.M. Westler, and J.L. Markley, "Elucidation of Protein Spin Systems and Determination of Heteronuclear Coupling Constants by Carbon-Proton-Proton Three-Dimensional NMR," J. Magn. Reson. 92, 434-438 (1991).  
     
  J. Fejzo, A.M. Krezel, W.M. Westler, S. Macura, and J.L. Markley, "Direct Cross-Relaxation NOESY (D.NOESY). A Method for Removing Spin-Diffusion Cross Peaks from Two-Dimensional NOE Spectra of Macromolecules," J. Magn. Reson. 92, 651-657 (1991).  
     
  J. Fejzo, A. M. Krezel, W.M. Westler, S. Macura and J.L. Markley, "Refinement of the NMR Solution Structure of a Protein to Remove Distortions Arising from Neglect of Internal Motion," Biochemistry 30, 3807-3811 (1991).
 
     
  J. Fejzo, W.M. Westler, S. Macura, and J.L. Markley, "Strategies for Eliminating Unwanted Cross-Relaxation and Coherence Transfer Effects from Two-Dimensional Chemical Exchange Spectra," J. Magn. Reson. 92, 20-29 (1991).  
     
  J. Fejzo, W.M. Westler, S. Macura, and J.L. Markley, "Elimination of Chemical Exchange Mediated Spin Diffusion from Exchange Spectra of Macromolecules. Exchange Decoupled NOESY (XD-NOESY)," J. Magn. Reson. 92, 195-202 (1991).  
     
  S.N. Loh, C.W. McNemar, and J.L. Markley, "Detection and Kinetic Characterization of a Novel Proline Isomerism in Staphylococcal Nuclease by NMR Spectroscopy," In Techniques in Protein Chemistry II, (J.J. Villafranca, Ed.), Academic Press, New York, pp 275-282 (1991).
 
     
  J.L. Markley, "Stable-Isotope-Assisted Multinuclear NMR Investigations of Proteins," In Proteins - Structure, Dynamics and Design, (V. Renugopalakrishnan, P. R. Carey, I. C. P. Smith, S.-G. Huang, and A. C. Storer, eds.), ESCOM, Leiden, pp. 29-39 1991.
 
     
  J.L. Markley, P. Darba, J. Fejzo, A.M. Krezel, S. Macura, C.W. McNemar, E.S. Mooberry, B.R. Seavey, W.M. Westler, and Z. Zolnai, "Computational Aspects of Multinuclear NMR Spectroscopy of Proteins at NMRFAM," In Computational Aspects of the Study of Biological Macromolecules by Nuclear Magnetic Resonance Spectroscopy, (J. C. Hoch, F. M. Poulsen, and C. Redfield, Eds.), NATO ASI Series, Plenum Press, New York, pp 39-50 (1991).  
     
  J.L. Markley, E.A. Farr, and B. R. Seavey, "Appendix: Check List for Protein NMR Data to be Submitted for Publication of for Database Inclusion," J. Biomol. NMR 1, 231-236 (1991).
 
     
  D.C. McCain, W.M. Westler, and J.L. Markley, "A Two-Dimensional Technique for Chemical Shift Resolution in One-Dimensional NMR Images," J. Magn. Reson. 93, 181-183 (1991).
 
     
  W.R. Rypniewski, D.R. Breiter, M.M. Benning G. Wesenberg, B.-H. Oh, J.L. Markley, I. Rayment, and H.M. Holden, "Crystallization and Structure Determination to 2.5 A Resolution of the Oxidized 2Fe-2S Ferredoxin Isolated from Anabaena 7120," Biochemistry 30, 4126-4131 (1991).  
     
  B.R. Seavey, E.A. Farr, W.M. Westler, and J.L. Markley, "A Relational Database for Sequence-Specific Protein NMR Data," J. Biomol. NMR 1, 217-230 (1991).  
     
  L. Skjeldal, J.L. Markley, V.M. Coghlan, and L. E. Vickery, "Hydrogen-1 NMR Spectra of Vertebrate [2Fe-2S] Ferredoxins. Hyperfine Resonances Suggest Different Electron Delocalization Patterns from Plant Ferredoxins," Biochemistry 30, 9078-9083 (1991).  
     
  L. Skjeldal, W.M. Westler, B.-H. Oh, A. M. Krezel, H.M. Holden, B.L. Jacobson, I. Rayment, and J.L. Markley, "Two-Dimensional Magnetization Exchange Spectroscopy of Anabaena 7120 Ferredoxin. Nuclear Overhauser Effect and Electron Self-Exchange Cross Peaks from Amino Acid Residues Surrounding the 2Fe-2S* Cluster," Biochemistry 30, 7363-7368 (1991).
 
     
  B.J. Stockman, A.M. Krezel, J.B. Olson, E.S. Mooberry, and J.L. Markley, "Flavin Binding Site Geometry in Anabaena 7120 Flavodoxin. Progress in Determining the Flavodoxin Solution Structure," In Flavins and Flavoproteins 1990, (B. Curti, S. Ronchi, and G. Zanetti, Eds.) Walter de Gruyter, Berlin, pp 377-380 (1991).  
     
     
  1990  
     
  A.T. Alexandrescu, A.P. Hinck, and J.L. Markley, "Coupling Between Local Structure and Global Stability of a Protein: Mutants of Staphylococcal Nuclease," Biochemistry 29, 4516-4525 (1990).  
     
  A.T. Alexandrescu, S.N. Loh, and J.L. Markley, "Chemical Exchange Spectroscopy Based on Carbon-13. Applications to Protein Folding and Enzymology," J. Magn. Reson. 87, 523-535 (1990).
 
     
  J. Alonso, C. Arus, W.M. Westler, and J.L. Markley, "Two-Dimensional Spectra of Intact Tissue: Homonuclear Hartmann-Hahn Spectroscopy Provides Increased Sensitivity and Information Content as Compared to COSY," Magn. Reson. Med. 15, 142-151 (1990).  
     
  J. Fejzo, W.M. Westler, S. Macura, and J.L. Markley, "Elimination of Cross-Relaxation Effects from Two-Dimensional Chemical Exchange Spectra of Macromolecules," <