Brian F. Volkman, Ph.D.

My efforts are divided into two main areas: core research at NMRFAM and collaborative projects with a number of investigators outside NMRFAM. Core research projects generally serve to advance the state of the art in biomolecluar NMR techonology. Collaborative projects have in common the application of standard NMR techniques to structural problems of biological interest.

Recent projects involve measurement and analysis of dipolar couplings on paramagnetically aligned proteins and nucleic acids and structure determinations of a variety of different proteins. These projects utilize multidimensional NMR methods on the 5 Bruker DMX spectrometers at NMRFAM, and have required the development or implementation of pulse programs for various triple-resonance experiments, ¹⁵N relaxation measurements, and quantitative J-correlation experiments. Summaries of a selection of my core and collaborative research projects are listed below, and a complete list of my publications is also available.